Archive for the 'Big Pharma' Category

A Short Drive with Healthy Skepticism’s Dr. Peter Mansfield

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Late on Wednesday afternoon, a picture perfect summer day in New York, I found myself waiting in the baggage claim area of La Guardia airport for Flight 360 from Chicago. I was there to meet Dr. Peter Mansfield of Australia’s Healthy Skeptism and to take him to the Wales Hotel in Manhattan. It would be a brief opportunity to talk to one of the world’s leading critics of pharmaceutical promotion.

Professor Mansfield had told me to look up his picture on Google Images and there was doubt it was him when he walked into the thicket of limousine drivers surrounding the baggage claim area. I soon learned that he was in the 7th week of a 9 week trip around the world that included 23 major metropolitan areas. No wonder he looked a bit tired. He had travelled in Europe (mentioning Switzerland, Italy, Germany, Spain and England), had come back to the US, was now in New York to speak at Mount Sinai Medical School, would then travel to San Francisco, Seattle, Sydney and Hobart before returning home sometime after June 25th. It seemed a Herculean task and he had been doing this for 25 years. [Medicamentos Madrid has a copy of his slide show presentation posted]

On our way to the car, Dr. Mansfield spoke about the Healthy Skepticism website which has links to 14,001 references on pharmaceuticals. The site is very thorough and relatively easy to navigate. Healthy Skepticism also offers a free monthly newsletter and a Fora where members can post messages.

As we drove out of the airport he told me he has been working on a reform proposal to address the problems of misleading drug advertising. Among the elements of this proposal were to 1. Increase regulation of drug promotion; 2. Improve medical decision making; 3. Redesign the incentives for doctors; and 4. Redesign the incentives for drug companies. He spoke of the need for doctors to be educated about their own biases. “Doctor’s don’t like to think that they are subject to bias,” he told me. And he then made a point of his own interest in hearing criticisms of their proposals; “that’s the only way they will get better.”

How did he propose to bring about these reforms? He leaned over conspiratorially and said: “With laughter! You can get people to see things with laughter that you cannot do in other ways.” Then, more seriously, he compared political processes to earthquakes. For a long time steam builds up until finally something dramatic happens and there is a break. This is the time when you need to present the politicians with a well-worked out plan. How could one build up such steam? Who were the natural constituencies of the reform plan? “Well, anyone who thinks that now - or in the future - they might get sick. [A smile] And all the employees of the pharmaceutical industry, except a very small group at the top, will want to see that they are doing the right thing. Reform is in their interest.”

I had wanted to ask if he really felt that misleading promotion was the main problem with the pharmaceutical industry, but by this time the New York City traffic had taken us near Mount Sinai Medical School and the Wales Hotel. He had to be up the next morning for an 8AM lecture and so it seemed time to end. As we parted he told me that his home town of Wilunga, where he worked as a GP, had only three thousand inhabitants “and would fit easily into one of these large buildings here.” Unloading his luggage we shared a bit about our families. Doctor Mansfield and his wife had three daughters: twins aged 18 and a 16 year old. “When I was in Sweden,” he told me, “and I told them I had 3 daughters in 18 months they asked, With how many women?” We laughed and said good-bye, exchanging cards and ideas. I mused on the idea of travelling for 9 weeks to 23 cities, entrusting yourself to complete strangers (as I was to him), getting to know them briefly and then moving on. This is political organizing or - as Dr. Mansfield might put it - building up steam.

Direct to Consumer Advertising (DTCA)

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Direct to consumer advertising (DTCA) of prescription medications is a relatively new and controversial marketing practice. Public health researchers and sociologists are beginning to explore the possible impact of these marketing practices on the epidemiology of some diseases. Is it possible that this marketing strategy propels the social construction of targeted disorders, like depression? For example, advertisements bring attention to specific symptoms (i.e., loss of interest or pleasure) and encourage consumers to label such symptoms as a disease (i.e., depression). Furthermore, is it possible that this approach to disorder construction has profound implications for public health? Advertisements stimulate the rapid uptake of new medications that may have unforeseen harmful effects and have targeted a specific audience that perpetuates disparities in access to care.


Web Resources:

Healthy Skepticism, one of the best sites for critical thinking on the pharmaceutical industry offers an extensive bibliography concerning DTCA on their website.

Disease mongering by the pharmaceutical industry has received a good deal of attention over the past few years. Lynn Payer’s Disease-Mongers: How Doctors, Drug Companies, and Insurers are Making You Feel Sick is a clear and passionate critique of how the “medical industrial complex” makes healthy people sick. A shorter introduction can be found in the 2004 article by Ray Moynihan, Iona Heath and David Henry’s article, Selling Sickness: The Pharmaceutical Industry and Disease Mongering, (British Medical Journal, April 13, 2004). A more recent collection of articles on the topic is listed on Anne T.-V’s blog.

For a look at DTCA related to Irritable Bowl Syndrome and women’s health see the Our Bodies Ourselves website.

DTC Perspectives, a pharmaceutical trade journal provides the industry point of view on DTC. The journal can be downloaded for free and makes very interesting reading.

The Center for Drug Evaluation and Research site for FDA has survey results related to DTCA.

No Free Lunch: Saying No to Drug Reps

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Under the banner “Just Say No to Drug Reps” the No Free Lunch campaign challenges doctors to give up their dependency on drug companies.

The site uses a alcoholism motif, beginning with a modified CAGE screening test:

  • Have you ever prescribed Celebrex?
  • Annoyed by people who complain about lunches & free gifts?
  • Is there a medication loGo on the pen you are using right now?
  • Do you drink your morning Eye-opener out of a Lipitor coffee mug?

Two or more “yes” answers may indicate a problem. But fortunately the campaign can help you with your dependence problem.  Visitors can take a pledge to abstain from accepting gifts from drug companies and be listed on a “drug free doctor” database. There is even a “pen amnesty”!

No Free Lunch is the brainchild of Dr. Bob Goodman, a New York internist.  Among the other resources on the site are:

So, it’s really not all that complicated to deal with drug representatives. Just say no.